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Our Pipeline

Dragonfly's novel Cytokine and TriNKET® immune engagers work in autoimmune disease, oncology, neuro-inflammation and other disease areas, directly and indirectly harnessing NK cells, CD8+ T cells and gd T cells to kill disease targets, and improving the outcomes of other immunotherapy approaches like T-cell therapies.

Dragonfly’s pipeline is robust and continues to grow both internally and with BMS, Merck, AbbVie, and Gilead

DF1001 (HER2-targeting)         
Clinical trial ID: NCT04143711

TriNKET®

Phase 3

Platform

Discovery

Preclinical

Phase 1

Phase 2

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Dragonfly Internal

Multiple candidates

TriNKET®

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DF6215 (IL-2-targeting)

Clinical trial ID: NCT06108479

CYTOKINE

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DF9001 (EGFR-targeting)

Clinical trial ID: NCT05597839

TriNKET®

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DF6002 (IL-12-targeting)     

Clinical trial ID: NCT04423029

CYTOKINE

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Phase 3

Platform

Discovery

Preclinical

Phase 1

Phase 2

BMS + Dragonfly Partnered

DF4001 (licensed)

TriNKET®

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DF2001 (CD33-targeting)   
Clinical trial ID: NCT04789655

TriNKET®

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DF5008 (licensed)

TriNKET®

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DF2200 (licensed)

TriNKET®

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Multiple candidates

TriNKET®

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DF2500 (licensed) - Neurology

TriNKET®

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Phase 3

Platform

Discovery

Preclinical

Phase 1

Phase 2

Merck + Dragonfly Partnered

DF8001 (licensed)

TriNKET®

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DF8101 (licensed)

TriNKET®

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Multiple candidates

TriNKET®

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Phase 3

Platform

Discovery

Preclinical

Phase 1

Phase 2

AbbVie + Dragonfly Partnered

DF4101 (licensed)

TriNKET®

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Multiple candidates

TriNKET®

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Phase 3

Platform

Discovery

Preclinical

Phase 1

Phase 2

Gilead + Dragonfly Partnered

Multiple candidates

TriNKET®

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